Uruguay v Colombia

Colombia are fifth in World Cup qualification, behind Uruguay on goal difference. They began the Copa with a tight win over Ecuador, confirming a bright start to the reign of new coach Reinaldo Rueda. Subsequent results, though, have not been impressive. The defeat to Brazil was controversial, while the loss to Peru and the draw with Venezuela were plain disappointing. They are simply not the same creative force in the absence of James Rodriguez.

Players to watch:

Uruguay, of course, are spearheaded by the old attacking firm of Atletico Madrid's Luis Suarez and Manchester United's Edinson Cavani. The future, though, belongs to Real Madrid's Federico Valverde, the motor of the side with his lung power and range of passing from midfield.

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Aside from James' absence, Colombia will be missing another key player. Juan Cuadrado is suspended, and will be hard to replace. His absence makes a tight game all the more likely, in which Colombia hope that Wilmar Barrios can be as effective as he was against Brazil in his defensive midfield role.

Head-to-head:

Uruguay have won 20 matches, lost 13 and drawn nine matches in 42 times they met Colombia. The last meeting ended in a 3-0 win for Uruguay in November last year.