If you suffer from seasonal allergies, you are not alone. Many people turn to oral antihistamines or montelukast for relief, but research shows that nasal sprays are far more effective. A systematic review of 35 clinical trials compared nasal sprays and oral medications in managing seasonal allergic rhinitis in teens and adults. The results were clear: nasal preparations outperformed pills across all measures, including symptom control and quality of life.

Nasal steroids provided the most significant benefit, especially when compared to montelukast. Nasal antihistamines also performed better than oral antihistamines, making sprays the top choice for treating allergies.

For mild-to-moderate symptoms that come and go, nasal antihistamines work quickly—often within 15 minutes—and can be used as needed. For persistent or severe symptoms, nasal steroids are more effective but require consistent daily use. If symptoms remain uncontrolled with one spray, combining nasal steroids with nasal antihistamines provides better relief than adding oral medications.

While many patients prefer pills, nasal sprays clearly deliver better results. If you are struggling with allergies, talk to your healthcare provider about switching to a nasal preparation.

Source: Journal of Allergy and Clinical Immunology