Bangladesh lost four wickets in their first seven overs in a hapless reply to South Africa's mammoth first innings of 575-6 at stumps Wednesday on day two of the second and final Test in Chattogram.

The hosts were 38-4 when bad light forced an early end to play, with Mominul Haque (six) and Najmul Hossain Shanto (four) resuming on Thursday.

Bangladesh trail by 537 runs after a commanding performance by the visitors that gifted maiden Test centuries to three batsmen including Tony de Zorzi, who was dismissed before lunch on 177.

Kagiso Rabada struck in the first over after the change, cutting off Shadman Islam for a duck when the left-hander edged a delivery going down the leg side.

Zakir Hasan also edged to the wicketkeeper playing a Rabada length ball outside off, departing for two.

Mahmudul Hasan Joy top-scored with 10 before falling to Dane Paterson while driving an outside-off delivery but managed only a thick edge to Aiden Markram at the second slip.

Hasan Mahmud came early as an intended nightwatchman but was fooled by sharp turn from Keshav Maharaj in the spinner's first over.

South Africa's total was their second-highest against Bangladesh behind 583-7 at the same venue in 2008.

Wiaan Mulder (105 not out) joined De Zorzi and Tristan Stubbs (106) to make his maiden hundred on a pitch offering little help to the bowlers.

Senuran Muthusamy was unbeaten at the declaration for 68 off 75 balls with five fours and two sixes, his Test best.

Ryan Rickelton was the only batsman to fall in the second session when he edged a Nahid Rana delivery shaping away from his body to the wicketkeeper, departing for 12.

Left-arm spinner Taijul Islam pegged back the visitors in the morning with three wickets in three overs, claiming his second five-wicket haul of the series.

He toppled David Bedingham's leg stump to end a 116-run stand for the third wicket with De Zorzi.

Bedingham departed after a brisk 59 off 78 balls that contained two fours and four sixes.

His wicket prompted a mini-collapse as De Zorzi swiped across the line and was trapped lbw by Taijul to leave South Africa 391-4.

In all, the opener smashed four sixes and 12 fours in his 269-ball knock.

South Africa won the opening Test inside four days with fast bowler Rabada taking 6-46 in the second innings.

Bangladesh have played 24 Tests in Chattogram but won only two with seven drawn.

Mulder hits century as SA declare at 575 for six 

Wiaan Mulder launched Taijul Islam for a six to get to his first Test century as South Africa declared their first innings at 575 for six. 

Mulder was unbeaten on 105 off 150 deliveries while Senuran Muthusamy was bating on 70 off 75 deliveries when the call for declaration came.

No kore wickets fell after Tea with the partnership having reached 154 off 31 overs. 

Bangladesh will start their innings with five runs, as penalty to South Africa for running on the pitch during their batting innings.

Tea, Day 2, SA 527 for six

South Africa went to Tea on the Second Day of the second Test in Chattogram 527 for six, Wiaan Mulder batting on 78 and Senuran Muthusamy unbeaten on 47.

The only wicket to fall after Lunch was that of Ryan Rickelton (12), caught by the wicketkeeper Mahidul Islam off pacer Nahid Rana. The five other wickets were taken by Taijul Islam.

Mulder and Muthusamy have already added 104 runs for the seventh-wicket partnership in 21.4 overs.  

Taijul Islam celebrates one of his five wickets in the first innings against South Africa in Chattogram. Photo: Firoz Ahmed

Lunch, Day 2: SA 413 for five

Taijul Islam took three wickets in space of five runs but South Africa moved past 400 on the second morning of the second Test against South Africa in Chattogram on Wednesday.

The left-arm spinner, who had got eight wickets including a five-for in the Dhaka Test which Bangladesh lost by seven wickets, took the two other wickets to fall on the opening day when the Proteas had scored 307 for two.

Taijul has now 14 five-wicket hauls in 49 Tests.

David Bedingham was the first to fall, bowled by Taijul on 59 as the Proteas lost their first of the morning on 386. 

Five runs later, Tony de Zorzi's marathon knock came to an end at 177, pinned in front by Taijul before first Test's centurion, Kyle Verreynne was trapped in front by the left-armer without adding to the score.

At Lunch, South Africa were 413 for five with Ryan Rickelton batting on 11 and Wiaan Mulder unbeaten on 12.