The Copa America is down to the final four with a pair of fascinating semifinals and favourites Argentina hoping they can win their third straight major title.

The Argentines, world champions and defending Copa title holders, open the semifinal action when they face surprise package Canada in New Jersey, with the match kicking off at 6:00am Bangladesh time tomorrow.

Tied on 15 Copa America titles with Uruguay, Argentina are hoping to become the most successful nation in the tournament's history.

The Albiceleste needed penalty shoot-out heroics from their goalkeeper Emiliano Martinez to get past Ecuador in the last eight and while Lionel Scaloni's team have yet to really hit top gear they start as clear favourites against Canada.

American coach Jesse Marsch has made an instant impact with Canada, taking over in mid-May and quickly implementing his high-energy, pressing style to great effect.

Marsch, who was reported to be close to taking over as USA coach before the decision last year to re-hire Gregg Berhalter, has had the last laugh as his team have produced a memorable run to the last four while the Americans failed to get out of their group.

Canada got past a Venezuela team that had won all three of their group stage games, winning on penalties at the end of a pulsating encounter on Friday.

However, they know that Lionel Messi and Argentina represent a very different proposition.

The teams met in the opening group game of the tournament with Argentina winning 2-0, but there is no shortage of confidence in Marsch's team.

"It's going to take everything," said Bayern Munich wing-back Alphonso Davies.

"Going into this game, we know what's on the line. We win and go forward, we lose and go home. They're going to come out with everything. We're hungrier than ever, we expect a battle -- as they should," he said.

Three of the four quarterfinals were decided on penalties, but Marsch insists his team will play their usual attacking style.

"The game against Argentina will have to be the best we've ever played ... We're not going to sit back and just try to defend. We will be aggressive. We're going to try to play the way we want to play and see if we can keep it up," he promised.

Argentina's line-up remains largely the one which triumphed in the World Cup in Qatar in 2022 although Messi, troubled by a hamstring strain, has yet to perform anywhere near the level he showed in that tournament.

But the midfield is packed with quality options and striker Lautaro Martinez has picked up four goals while the defence, marshalled by Lisandro Martinez, has looked solid.

The winners of the first semifinal will play in the final on July 14 against the winners of the second semifinal between Uruguay and Colombia.