At the Emirates Stadium, Brazilian striker Jesus finally found the back of the net on home turf for the first time in 2024.
Arsenal failed to take advantage of Liverpool's rare stumble as the Gunners were kept at bay on a frustrating afternoon at the Emirates Stadium.
Expertly taken goals from Nicolas Jackson, captain Enzo Fernandez and Cole Palmer earned Chelsea a 3-0 home win over Aston Villa on Sunday, lifting them to joint second in the Premier League table.
Enzo Maresca does not believe his Chelsea side are in the Premier League title race despite an impressive start to the season in his first campaign at Stamford Bridge.
Arteta had demanded a dynamic display from his team ahead of their trip to the Jose Alvalade stadium and they responded in style.
Mikel Arteta's Gunners remained provisionally third in the standings on 18 points, with the two teams above them -- Manchester City and Liverpool -- playing later on Saturday. Newcastle climbed to eighth on 15 points.
Bukayo Saka became the youngest Arsenal player to score 50 Premier League goals when he returned from a hamstring injury in Sunday's 2-2 draw with Liverpool, but the winger was disappointed to drop two points after being on the verge of a crucial win.
Arsenal bounced back from their embarrassment at Bournemouth as an own goal from Shakhtar Donetsk keeper Dmytro Riznyk gave the Gunners a 1-0 win in the Champions League on Tuesday.
Saturday's 2-0 loss at Bournemouth brought Arsenal's unbeaten start to the league season to a shuddering halt.
Manchester City hold the destiny of the Premier League title in their hands after Arsenal and Liverpool stumbled to shock defeats on Sunday.
Arteta's side would have gone back to the top of the table with a victory at the Emirates Stadium.
Arsenal's Premier League title hopes suffered a massive blow as Aston Villa struck twice in the closing stages to boost their top four bid with a dramatic 2-0 win at the Emirates Stadium on Sunday.
Pep Guardiola said Manchester City are in a privileged position to be fighting to defend a treble of trophies after beating Luton 5-1 to go top of the Premier League on Saturday.
As the title race approaches its final stretch, leaders Arsenal face a potentially decisive reunion with their former boss Unai Emery.
The former Tottenham striker enjoyed a prolific record in north London derbies and a summer change of scenery made no difference.
Tuchel's team are on the brink of surrendering the German title for the first time in 12 years after a brutal domestic campaign.
The super computers and number crunchers still don't fancy Arsenal's chances of winning a compelling three-way Premier League title race despite, on current form, the London club being the best team in England.
"We're all buzzing, we know the win takes us back on top. We're building momentum," said Saka.
"I've been in the tunnel playing in a different shirt and looking at the Invincibles, You had a feeling 'tonight is going to be really tough'. Hopefully we can create that," Arteta said