Kevin De Bruyne has signed for Napoli as a free agent after being released by Manchester City, the Serie A champions' president Aurelio De Laurentiis confirmed on Thursday.
A 2–0 victory over Cagliari in the final round ensured they stayed ahead of Inter Milan, sending the Campania region into rapturous celebration.
Antonio Conte has dragged Napoli back from disaster and restored them to the top of Serie A but his future at the Scudetto winners is in doubt even after a triumphant season.
With second-placed Inter Milan also playing out a 2-2 draw against Lazio in a simultaneous kickoff, Napoli will head into their final match against Cagliari with a one-point advantage.
Antonio Conte's team are one step closer to a second league title in three seasons thanks to Giacomo Raspadori's well-struck free-kick in the 24th minute of a match which was briefly stopped by home fans' fiery protest against the league following the death of a beloved club physi
Two first-half goals from Scott McTominay helped Napoli to a 2-0 home success, sending them above defending champions Inter Milan in the standings after Simone Inzaghi's side stumbled to a shock 1-0 home loss against AS Roma.
Scotland midfielder McTominay nodded home his 10th goal in all competitions this season from Giacomo Raspadori's cross in the 72nd minute to save Napoli's blushes after a drab display in northern Italy.
Belgium striker Lukaku has scored 12 times and set up 10 more in Italy's top flight this season and has been key to Napoli's battle with reigning champions Inter for the league title.
The win moved Napoli three points behind leaders Inter Milan, who beat Udinese 2-1, while third-placed Atalanta lost 1-0 at Fiorentina.
Real Madrid romped to a 4-2 win over Napoli on Wednesday to qualify in first place from their Champions League group.
Mazzarri's team are still seven points behind leaders Inter Milan who travel to Turin on Sunday for the weekend's big match at second-placed Juventus
Inter Milan and Juventus face off on Sunday in a clash between Serie A's two title favourites and historic rivals, as Walter Mazzarri begins his second reign at troubled Napoli.
Napoli continued their struggles on home turf with Sunday's shock 1-0 defeat to Empoli which left the Serie A champions already well off the pace in this season's title race.
Khvicha Kvaratskhelia helped put Napoli's Serie A title defence back on track with a brace in Saturday's 3-1 win at Verona which moved the champions four points behind leaders AC Milan.
Real scored the winner in the 78th minute as a stunning long-range shot from Federico Valverde cannoned off the crossbar straight onto the back of the flailing Meret's head before deflecting into his own goal.
Inter Milan laid down an early title marker on Saturday by handing out a 5-1 derby hammering to AC Milan and going it alone at the Serie A summit, while champions Napoli were held 2-2 at promoted Genoa.
Victor Osimhen netted his third goal of the season from the penalty spot 15 minutes into Napoli's first home match since lifting the league title in front of their fans for the third time back in June.
Victor Osimhen started where he left off for Napoli with a brace in Saturday's 3-1 victory at promoted Frosinone which gave the champions a winning start to their Serie A title defence.
Napoli ended their 33-year wait for a Serie A title last season in spectacular fashion by securing it with five games to spare, but with new management and recent history against them, retaining it could be a very tough task. They begin their title defence at promoted Frosinone on Saturday.
