Kevin De Bruyne has signed for Napoli as a free agent after being released by Manchester City, the Serie A champions' president Aurelio De Laurentiis confirmed on Thursday.
A 2–0 victory over Cagliari in the final round ensured they stayed ahead of Inter Milan, sending the Campania region into rapturous celebration.
Antonio Conte has dragged Napoli back from disaster and restored them to the top of Serie A but his future at the Scudetto winners is in doubt even after a triumphant season.
With second-placed Inter Milan also playing out a 2-2 draw against Lazio in a simultaneous kickoff, Napoli will head into their final match against Cagliari with a one-point advantage.
Antonio Conte's team are one step closer to a second league title in three seasons thanks to Giacomo Raspadori's well-struck free-kick in the 24th minute of a match which was briefly stopped by home fans' fiery protest against the league following the death of a beloved club physi
Two first-half goals from Scott McTominay helped Napoli to a 2-0 home success, sending them above defending champions Inter Milan in the standings after Simone Inzaghi's side stumbled to a shock 1-0 home loss against AS Roma.
Scotland midfielder McTominay nodded home his 10th goal in all competitions this season from Giacomo Raspadori's cross in the 72nd minute to save Napoli's blushes after a drab display in northern Italy.
Belgium striker Lukaku has scored 12 times and set up 10 more in Italy's top flight this season and has been key to Napoli's battle with reigning champions Inter for the league title.
The win moved Napoli three points behind leaders Inter Milan, who beat Udinese 2-1, while third-placed Atalanta lost 1-0 at Fiorentina.
Osimhen tapped in at the far post to give his team a 40th minute lead
Napoli have had an impressive season so far, currently with a 15-point lead over second-placed Inter Milan in Serie A, and have won seven straight domestic league games, scoring at least two goals in each.
Simone Inzaghi's side stay second and are three points ahead of local rivals AC Milan, who beat Monza 1-0 earlier on Saturday, but are a long way behind rampant Napoli after their 2-0 win at Sassuolo on Friday.
It looks only a matter of time before Luciano Spalletti's rampant side secure a Scudetto dreamed of by Napoli fans since the days of Diego Maradona
A 33-year wait for the league crown looks closer to ending for Napoli
AC Milan's crisis threatens to deepen as the champions head into Sunday's derby with Inter, miles off the Serie A title pace and in a battle to reach next year's Champions League.
Serie A title fever is sweeping Naples as the football-mad city hopes that rampant Napoli will end more than three decades of waiting to be crowned kings of Italy.
Napoli must seize their "unprecedented opportunity" to win the Scudetto after reaching 50 points at the halfway mark of the Serie A season by beating Salernitana, said Luciano Spalletti.
Dazzling duo Victor Osimhen and Khvicha Kvaratskhelia have Napoli dreaming after starring in a five-goal massacre of Juventus which made them clear favourites to claim a first Serie A title in over three decades.
Napoli stamped their authority on the Serie A title race on Friday by thrashing Juventus 5-1 and moving 10 points clear of the chasing pack.