Neymar was out for more than a year until last month following right knee surgery.
The Brazilian superstar lasted just 26 minutes as a second-half substitute before limping off with an apparent right hamstring strain in Monday's 3-0 AFC Champions League Elite win over Esteghlal.
The evening ended on a sour note for Al-Hilal when Neymar, who returned two weeks ago from a year out due to a ruptured cruciate ligament, was replaced 29 minutes after his introduction from the bench due to injury.
The former Barcelona and Paris Saint-Germain attacker had not played since rupturing his meniscus and anterior cruciate ligament in his left knee while on international duty in October last year.
"Happy to be back in the group," Neymar posted on Instagram, with pictures of him running and kicking the ball, watched by Al Hilal's Portuguese coach Jorge Jesus.
Brazil coach Dorival Junior called for Neymar to be given as much time as he needs to make a complete recovery from a knee injury that has sidelined him for almost a year.
Neymar is set to miss the start of the next Saudi Pro League season as he recovers from a serious knee injury, Al Hilal's coach said Tuesday.
The country of Pele, Garrincha and Ronaldinho, which once wowed the world with its 'samba' style, has not won the World Cup since 2002. Nor has it produced a Ballon d'Or winner since Kaka in 2007.
Jorge Jesus' side, top of the Saudi league and still alive in the King's Cup and Asian Champions league, are bidding for a quadruple of trophies this season.
Paris Saint-Germain coach Unai Emery remains optimistic that superstar Neymar will be fit to face Real Madrid in their do-or-die Champions League clash despite suffering an ankle injury in Sunday's 3-0 victory over Marseille.
Former Real Madrid midfielder Guti Hernandez believes that PSG forward Neymar needs to join Real Madrid to achieve new heights in his career.
French club Dijon come up with witty joke regarding PSG following the Paris outfit's defeat to Real Madrid in the Champions League.
Neymar has not been affected by the rumours linking him with a move to Real Madrid, his Paris Saint-Germain teammate Marquinhos insists ahead of the sides' Champions League showdown.
With Cristiano Ronaldo on one side and Neymar on the other, Wednesday's heavyweight Champions League showdown between Real Madrid and Paris Saint-Germain sees two of the game's biggest global superstars collide.
Brazil coach Tite defends his star striker Neymar against criticism in the penalty controversy that has engulfed the Paris Saint-Germain superstar and teammate Edinson Cavani.
Brazil right back Dani Alves says that he had nothing to do with Neymar’s move to PSG but believes that the Brazil forward had to get out of Lionel Messi’s shadow.
Paris Saint-Germain coach Unai Emery calls on fans to show Neymar more "affection", despite the Brazilian's excellent form since joining the Ligue 1 leaders.
Memphis Depay strikes a dramatic late winner as Lyon beat 10-man Paris Saint-Germain 2-1 to move within eight points of the Ligue 1 leaders.
Neymar nets four goals while Edinson Cavani becomes Paris St Germain's joint top scorer ever as the runaway Ligue 1 leaders demolish visitors Dijon 8-0 on Wednesday.