"Sergio Ramos has informed Sevilla FC that he will not stay next season," the club said in a statement.
Antoine Griezmann struck a hat-trick in a 3-0 win over 10-man Celta Vigo to help Atletico Madrid climb provisionally second, in hot pursuit of their city rivals.
Sergio Ramos has not played against Real Madrid since 2005 but on Saturday, his Sevilla team welcome the Spanish league leaders to the Sanchez-Pizjuan for a reunion.
Real Madrid legend Sergio Ramos's own goal handed his old enemy Barcelona a narrow 1-0 win over Sevilla on Friday in La Liga, taking the Catalans top of the table.
Sergio Ramos made his second Sevilla debut in a narrow win over Las Palmas, while Mason Greenwood played his first match for Getafe, on loan from Manchester United
Castro had been sceptical last month when it was reported that Ramos was keen to return to his boyhood club.
Veteran former Spain defender Sergio Ramos said Monday he was returning to his home-town club Sevilla after 18 years away.
Sergio Ramos, Jordi Alba, Sergio Busquets, N'Golo Kante, Angel Di Maria and Roberto Firmino are also among the seasoned World Cup and Champions League winners being lined up for the Saudi Pro League, the source said.
Spanish defender Sergio Ramos is leaving French Champions Paris St Germain, the Ligue 1 club said on Friday.
Sergio Ramos has so often been Real Madrid's man of the moment but the captain saw the tables turn as his own goal helped his former club Sevilla to a 2-1 win over the La Liga leaders on Sunday, ending a record-breaking 40-game unbeaten run.
Real Madrid coach Zinedine Zidane paid tribute to his players' spirit after they battled back to beat Deportivo La Coruna 3-2 on Saturday and set a club record 35 games unbeaten in all competitions.
Real Madrid launched a staunch defence of star forward Cristiano Ronaldo on Tuesday, demanding respect for the three-time World Player of the Year amid allegations he hid millions of euros earned from image rights in tax havens.
Key defender and captain Sergio Ramos suffered a left knee strain in Spain's 2-0 World Cup qualifying win in Albania on Sunday.
Andres Iniesta reveals he wanted to take the penalty that Sergio Ramos missed in Spain's 2-1 Euro 2016 loss to Croatia on Tuesday.
Ivan Perisic strikes a sensational winner three minutes from time as Croatia end Spain's 14-game unbeaten run at the European Championship finals to top Group D with a 2-1 victory
Real Madrid's Sergio Ramos has set a new Champions League record by becoming the first defender to score in two finals.
Real Madrid's Sergio Ramos has set a new Champions League record by becoming the first defender to score in two finals.
Real Madrid defender Sergio Ramos admits he has been enjoying Barcelona's recent problems and believes his side's 2-1 win over them in the Clasico kick-started their slump.
Cristiano Ronaldo recovered from a missed penalty to score twice as Real Madrid beat luckless Real Sociedad 3-1 on Wednesday, easing the pressure on coach Rafael Benitez.