Reigning champions Inter came through what was supposed to be a tough test at the Stadio Olimpico with flying colours and are three points off the Scudetto pace with a game in hand.
Substitute Zaniolo decided a hard-fought encounter in Sardinia by stroking home Raoul Bellanova's cut-back in the 66th minute and moving Atalanta five points clear.
Edoardo Bove has had a defibrillator fitted after the Fiorentina midfielder's on-pitch cardiac arrest earlier this month, according to widespread Italian media reports on Tuesday.
Fiorentina earlier remained on Napoli's heels after their 1-0 home win over Cagliari in their first league match since midfielder Edoardo Bove's sudden collapse last weekend.
Edoardo Bove is conscious and alert in hospital after his sudden collapse which caused Fiorentina's match with Inter Milan to be called off, the Serie A club said on Monday.
Fiorentina's Serie A match with Inter Milan was stopped on Sunday after midfielder Edoardo Bove suddenly collapsed to the ground.
"It's too early to talk about the title. All we can do is look out for how we develop as a team, work to improve and win every match we play. But now is not the moment to talk about the title," said Lukaku.
Juventus remain the only unbeaten side in Serie A but their seventh draw of the season means they remain sixth in the standings and are now three points behind leaders Inter Milan. Milan stay seventh, six points behind Juve, though they have played one game fewer.
Simone Inzaghi's side are provisionally ahead of Napoli after netting all five of their goals in the opening 45 minutes at the Stadio Bentegodi through a Marcus Thuram brace and further strikes from Joaquin Correa, Stefan de Vrij and Yann Bisseck.
Inter and AC Milan on Friday rejected the project to modernise and restructure the iconic San Siro stadium which they share, city mayor Giuseppe Sala announced.
Victor Osimhen has been sidelined by Napoli after the team he fired to Serie A glory just a over year ago left him both off their squad list for the 2024/25 campaign and potentially in season-long limbo.
Belgium striker Lukaku completed a permanent move to Napoli from Chelsea on Thursday, ending a long period of limbo with the Blues.
Inter Milan thrashed Atalanta 4-0 on Friday to move provisionally top of Serie A, while Torino snatched a late 1-0 win at Venezia to continue their positive start to the campaign.
The futures of Napoli striker Victor Osimhen and England international Ivan Toney are set to dominate the final day of the European transfer window on Friday as Chelsea continue their frenzied pursuit of new signings.
Napoli have signed Romelu Lukaku from Chelsea, the Serie A club announced on Thursday, ending the Belgium striker's extended period in limbo with the Blues.
Poland goalkeeper Wojciech Szczesny on Tuesday announced he was retiring from football at the age of 34 less than two weeks after the end of his contract with Juventus.
"Winning is hard but staying up there is even harder. We had to bounce back after drawing at Genoa and we managed to do that," said Darmian to Sky Sport.
Napoli manager Antonio Conte apologised to the club's fans after his side were humbled 3-0 at Hellas Verona in Serie A on Sunday and said he took responsibility for the loss.
Inter Milan were denied a win in the opening match of their Serie A title defence on Saturday as late penalty drama left the champions with a 2-2 draw at Genoa.