"At approximately 10 pm on July 22, 2018, a man walking along Danforth Avenue fired shots at groups of people several times. Several people were struck. Two civilians were fatally injured," the Ontario Special Investigations Unit said.

The unit, which investigates police-involved shootings, said officers located the man on a cross street "and an exchange of gunfire took place."

"The man fled the area and was located deceased on Danforth Avenue," it said.

Toronto police chief Mark Saunders had said earlier that one of the victims was a young woman, and that a young girl was in critical condition. It put the number of wounded at 13.

The gunman, who police said was 29, was not identified by name and a motive for the shooting in a district of cafes and restaurants was not immediately known.

Officers, some armed with rifles, sealed off Danforth Avenue, Greektown's main street, after getting the call around 10:00 pm (0200 GMT Monday).

Witnesses reported hearing about 20 shots.

"There was a lot of shots. It would shoot, there'd be a pause, we heard more shooting, and then a pause and then more shooting," The Globe and Mail quoted John Tulloch, who was out for a walk at the time, as saying.

"There must've been 20, 30 shots, altogether. It was a lot. We just ran."

- People screamed, fled -

Jody Steinhauer told CBC News she was at a neighborhood restaurant with her family when she heard what sounded like 10 to 15 blasts of firecrackers.

She said she was told to run to the back of the restaurant.

"We started to hear people scream out front," Steinhauer told the broadcaster.

Ontario's new Premier Doug Ford called it a "horrific act of gun violence" and said his heart went out to the victims.

The incident comes with Canada's largest metropolis concerned over a surge of shootings. Canada traditionally has relatively low levels of gun violence, particularly compared with neighboring United States.

Mayor John Tory said Sunday night's firearms violence is "evidence of a gun problem" in Toronto.

"Guns are too readily available to too many people," Tory told a news conference.

Tory added that details of the latest incident remained sketchy and urged people to stay calm.

"We have to figure out what happened here. We don't know," he said.

Toronto Police statistics show that, to July 14, there had been a total of 220 shootings with 27 fatalities so far this year, against 196 with 17 deaths for all of 2017.

Last week, Toronto police started implementing the enforcement component of their "gun violence reduction plan." That includes around 200 additional officers on shift in particular neighborhoods between the hours of 7:00 pm and 3:00 am - when most shootings occur.

The Greektown shooting comes about three months after the city was shaken by the deaths of 10 people killed by a man with an apparent grudge against women who drove into them on a busy street in Toronto's north end.