Bayer Leverkusen will be without influential captain Lars Bender for Wednesday's crunch Champions League clash with Tottenham Hotspur at Wembley.

Right-back Bender, who won a silver medal with Germany at the 2016 Rio Olympics, is out with a bruised heel from Saturday's 2-1 comeback win at Wolfsburg in the Bundesliga.

Also out injured is Australian winger Robbie Kruse, although he is out of favour and has not featured in either the Bundesliga or Champions League this season.

But Leverkusen coach Roger Schmidt has Germany international Jonathan Tah and Turkey's Omer Toprak fit after injuries to strengthen his defence.

Leverkusen are third in Group E after drawing their first three games, just one point behind Spurs, with Monaco top.