Juventus starlet Moise Kean made his Serie A debut at the age of 16 and 265 days Saturday after replacing Mario Mandzukic in a 3-0 win over Pescara that tightened the champions' grip on the top of Serie A.

Juventus were cruising to a comfortable win against the league newcomers in Turin after goals from Sami Khedira, Mandzukic and Hernanes wrapped up a fourth consecutive league win to move them seven points ahead of Roma before the remaining weekend fixtures.

But coach Massimiliano Allegri gave fans an indication of a likely future star of the club when he sent Kean on for a long-awaited debut having stunned observers with several impressive performances for the club's under-19 side.

Kean, who turned 16 on February 28, had little time to get into his stride but showed some fancy footwork on his way to winning a corner that, on the stroke of full-time, was not given.

It was a brief yet promising cameo that will give fans around the world of seeing Kean -- of Ivorian heritage but who has played at all levels for Italy -- become the first player born after 2000 to play in the Champions League from next year.

He was not included in the club's 21-man squad list for the competition on September 1.

But Kean has already being watched by rival clubs in Europe, and Juventus CEO Beppe Marotta said he hopes Kean's agent doesn't have ideas.

"Playing at Juventus should be a point of pride for him. He's in the best possible place," Marotta told Mediaset Premium.

"If it comes down to money, that's a different story. His agent should reason with him, it shouldn't just come down to money."

Allegri added:"He has the chance to play alongside top players here. He has soak up what it's like to be part of a great squad. His attitude will make the difference."

Juventus travel to Sevilla on Tuesday in a bid to secure their last 16 ticket in the competition and Allegri added: "It's an important game for us because we have to win one of our last two games to go through."

Earlier, a second-half brace from Lorenzo Insigne boosted Napoli's hopes of maintaining Champions League football in a 2-1 win at Udinese that pushed the southerners up to fourth at six points behind Juve. It helped Napoli return among the top five.

Amid a seven-month goal drought, Insigne looked the last player to get his name on the scoresheet.

Playing despite a bout of flu and amid injuries to striker Arkaduisz Milik and Manolo Gabbiadini, Insigne turned on the style in 10 second-half minutes to claim his maiden league goals.

"It was obviously he was going for at least a brace," said coach Maurizio Sarri.

"I could see it in the way he reacted after hitting his first goal. He was reborn and about to become very dangerous every time he touched the ball."