Second seed Agnieszka Radwanska and former French Open finalist Simona Halep crashed out in the last 16 on another rain-hit day at Roland Garros on Tuesday.

Radwanska appeared to be cruising into the quarter-finals as she led unseeded Bulgarian Tsvetana Pironkova 6-2, 3-0 before play was suspended on Sunday, with the tournament then suffering its first washout in 16 years on Monday.

But the Pole, who was hampered by a right wrist injury, dropped 10 straight games either side of another rain delay on Tuesday as world number 102 Pironkova extended her best run in Paris.

Sixth seed Halep, beaten in the 2014 final by Maria Sharapova, suffered a 7-6 (7/0), 6-3 defeat to former US Open champion Samantha Stosur of Australia.

The Romanian was 5-3 up when their contest, also held over from Sunday, resumed on Court One, but Stosur broke Halep as she tried to serve out the first set before racing through the tie-break to seize control.

Stosur, the 2010 French Open runner-up, again broke her opponent to begin the second set before clinching a quarter-final berth courtesy of a second break.

The 21st seed will face Pironkova next, with the winner of that tie playing Spain's Garbine Muguruza or 108th-ranked American Shelby Rogers for a place in the final.

Meanwhile, World number one Novak Djokovic dropped the opening set to 14th seed Roberto Bautista Agut in Tuesday's last-16 French Open clash before rain interrupted play.

Top seed Djokovic lost his serve three times as Bautista Agut claimed the first set 6-3 in 37 minutes before the covers were pulled over Court Philippe Chatrier.