At the Emirates Stadium, Brazilian striker Jesus finally found the back of the net on home turf for the first time in 2024.
Arsenal failed to take advantage of Liverpool's rare stumble as the Gunners were kept at bay on a frustrating afternoon at the Emirates Stadium.
Expertly taken goals from Nicolas Jackson, captain Enzo Fernandez and Cole Palmer earned Chelsea a 3-0 home win over Aston Villa on Sunday, lifting them to joint second in the Premier League table.
Enzo Maresca does not believe his Chelsea side are in the Premier League title race despite an impressive start to the season in his first campaign at Stamford Bridge.
Arteta had demanded a dynamic display from his team ahead of their trip to the Jose Alvalade stadium and they responded in style.
Mikel Arteta's Gunners remained provisionally third in the standings on 18 points, with the two teams above them -- Manchester City and Liverpool -- playing later on Saturday. Newcastle climbed to eighth on 15 points.
Bukayo Saka became the youngest Arsenal player to score 50 Premier League goals when he returned from a hamstring injury in Sunday's 2-2 draw with Liverpool, but the winger was disappointed to drop two points after being on the verge of a crucial win.
Arsenal bounced back from their embarrassment at Bournemouth as an own goal from Shakhtar Donetsk keeper Dmytro Riznyk gave the Gunners a 1-0 win in the Champions League on Tuesday.
Saturday's 2-0 loss at Bournemouth brought Arsenal's unbeaten start to the league season to a shuddering halt.
Arsenal cannot afford to repeat the performance that led to Sunday's 2-1 loss at Fulham if they want to fight for the Premier League title, manager Mikel Arteta said.
Mikel Arteta's Gunners were top of the tree at Christmas for a second successive year but trail leaders Liverpool by two points at the halfway point of the season.
The Gunners are without five players for Thursday's match at home to West Ham.
Mikel Arteta said it is vital to look after fans as Premier League leaders Arsenal confirmed on Friday they will not be involved in a revised European Super League proposal.
Liverpool manager Juergen Klopp said he was unhappy with the home support during their 5-1 League Cup win over West Ham United and urged fans to give their tickets away if they are not in the "right shape" for the visit of Arsenal at the weekend.
Victory moved Arsenal a point clear of Aston Villa, who moved up to second on 38 points. Third-placed Liverpool are a point further behind ahead of their game against rivals Manchester United later on Sunday.
Unai Emery revealed he didn't shake hands with any members of the Arsenal coaching team after Aston Villa 's huge 1-0 win because Mikel Arteta was absent.
Unai Emery's men have now won 15 consecutive Premier Leagues at Villa Park and back-to-back victories over Manchester City and the Gunners have sparked hopes of an unexpected challenge for their first title since 1981.
Arsenal are back on top of the Premier League with ambitions to stay there as they host Wolves this weekend while champions Manchester City play faltering Tottenham.
The Gunners' 6-0 win was the biggest-ever victory by an English team against a French opponent in European competition.