Medvedev still leads their head-to-head 7-6, although the Italian Sinner has won six of their last seven meetings.
Top seed Swiatek, who won the title two years ago, showcased her all-court game in a straightforward 6-4, 6-1 win over Russian Liudmila Samsonova to open the evening session at Arthur Ashe Stadium and warned she was only going to improve.
The Russian looked out of sorts early on Centre Court as he lost the first set.
Medvedev, a semi-finalist last year, hit 16 aces in his 6-3, 6-4, 6-2 win over Aleksandar Kovacevic of the United States.
De Minaur had never got past the second round at the tournament before this year, winning just three of 10 matches.
Italy's Jannik Sinner destroyed defending champion Daniil Medvedev 6-1, 6-2 in just 69 minutes on Friday to reach the final of the ATP Miami Open, where he will take on Grigor Dimitrov.
Daniil Medvedev returned to action for the first time since his Australian final defeat on Tuesday with a straight sets win over Alexander Shevchenko in Dubai.
Medvedev feels ready to get back on court after spending the last seven days training in Dubai.
Since Stan Wawrinka won his only title in Melbourne in 2014, Novak Djokovic has picked up six trophies, Roger Federer has won two and Rafael Nadal has won one.
Alcaraz, returning to the same Arthur Ashe Stadium court where he lifted his first Grand Slam as a teenager a year ago, was always in control after Germany's Dominik Koepfer rolled his left ankle badly in the opening game
Medvedev battled back to defeat unseeded Christopher Eubanks in five sets and reach the last four at the All England Club for the first time on Wednesday.
The top seed won the key moments during the quarter-final on Centre Court to progress 7-6 (7/3), 6-4, 6-4 and will play Russian third seed Daniil Medvedev in the semi-finals
Women's top seed Iga Swiatek outclassed Spain's Sara Sorribes Tormo 6-2, 6-0 and Daria Kasatkina thumped Jodie Burrage 6-0, 6-2 to reach the third round before organisers worked to clear the backlog of first-round matches.
Djokovic racked up a men's record 23rd Grand Slam title with a third French Open triumph last month
The Russian added a first clay trophy to his 19-title collection with a 7-5, 7-5 win over Holger Rune in the Italian Open final in Rome.
Sinner had upset world number one and defending champion Carlos Alcaraz in Friday's semi-final, but the 21-year-old struggled in the heat against the fourth seed Medvedev, who triumphed 7-5, 6-3
Medvedev reached his fifth straight ATP final with a three-set victory over fellow Russian Karen Khachanov in the semi-finals of the Miami Open, just hours after the decision from the All England Club.
"I'm playing great. Of course today, the conditions today were pretty tough. Of course Daniil didn't play at his best, obviously," said Alcaraz
The 27-year-old, who won in Rotterdam last Sunday, convincingly ended his 35-year-old opponent's comeback heroics that saw Murray fight four three-set battles and overcome eight match points to reach the final in Doha
