Barca have now gone three games without a LaLiga win having picked up five points out of a possible 21, suffering defeats by Leganes and Las Palmas in their previous two home games. They are three points behind Atletico having played a game more.
Pedri sent the Catalans ahead but second-half goals from Rodrigo De Paul and Alexander Sorloth helped Diego Simeone's side move three points clear at the top of the table, having played one match fewer than Barca.
Diego Simeone's red-hot Atletico are one of the most in-form teams in Europe on an 11-game winning streak in all competitions and looking like a well-oiled machine with Antoine Griezmann, Julian Alvarez and Rodrigo de Paul firing on all cylinders.
La Liga leaders Barcelona stumbled 1-0 at home against Leganes on Sunday as they suffered another blow in the Spanish title race.
Diego Simeone's side have been in fine form and continued their winning run across all competitions with a deserved home triumph, pulling provisionally level with league leaders Barcelona.
Real missed the chance to move above leaders Barcelona in LaLiga as they stay second on 37 points from 17 matches, one behind the Catalans who host Leganes on Sunday when Atletico, in third place on 35 from 16 games, welcome Getafe.
The 23-year-old was forced off with a muscle injury in their 4-0 thrashing of Osasuna at the Bernabeu earlier in November
"We changed the position of the forwards, with Mbappe outside and he did well, like Vinicius inside," said Ancelotti.
Raphinha and Robert Lewandowski's goals put the Catalans in a healthy position but Marc Casado's red card in the 82nd minute helped Celta start the fightback to snatch a point.
Ernesto Valverde, who is rumoured to be the prime target for the Barcelona managerial job next season says goodbye to his current club Athletic Bilbao on Wednesday.
Midfielder Koke has signed a contract extension to stay at Atletico Madrid until June 2024, the club confirms.
Barcelona's inconsistency over the season had cost them the La Liga title, coach Luis Enrique says.
Real Madrid have all they can ask for with just one La Liga game of the season to go and that is the destiny of the title in their own hands, coach Zinedine Zidane said on Saturday.
Real Madrid move to within one point of winning La Liga as Cristiano Ronaldo strikes twice to down Celta Vigo 4-1 on Wednesday.
Zinedine Zidane insisted his Real Madrid stars don't feel like champions yet, as his side close in on a potential double.
In-form striker Cristiano Ronaldo will try to take Real Madrid to the brink of the Spanish title on Wednesday against Celta Vigo.
Valencia on Thursday named former Villarreal manager Marcelino as coach for next season, as the fallen giants of La Liga plot a revival in fortunes after two disappointing seasons and a slew of managers.
Tiny Leganes moved to the brink of safety in their first season in La Liga by thrashing Real Betis 4-0 helped by a sensational goal from 50 metres by Brazilian Gabriel Pires on Monday.
Real Madrid produce a ruthless first-half display to thrash already-relegated Granada 4-0 and remain on course for a first league title in five years, while Barcelona hammer Villarreal 4-1.