Guardiola's side have lost eight of their past 11 games in all competitions following the devastating 2-1 defeat in the Manchester derby at the Etihad Stadium on Sunday.
Manchester City have won just once in 11 games in all competitions, a run that includes eight defeats.
Enzo Maresca's high-flying Chelsea beat Brentford 2-1 at Stamford Bridge to close to within two points of long-time leaders Liverpool, who have 36 points.
Josko Gvardiol's first-half goal appeared to have won the game for the Premier League champions but Bruno Fernandes levelled from the penalty spot in the 88th minute and the impressive Amad Diallo poked home the winner two minutes later.
Guardiola's side have won once in their last 10 matches in all competitions, sit fourth in the Premier League, eight points behind leaders Liverpool, and are in danger of a humiliating exit from the Champions League.
However, profits dipped from £80.4 million in City's treble-winning 2022-23 campaign to £73.8 million last season.
Manchester City were plunged further into crisis on Wednesday after falling to a 2-0 defeat at Juventus which threatens their chances of reaching the last 16.
The English champions stand accused of 80 breaches of financial rules between 2009 and 2018, plus a further 35 of failing to cooperate with a Premier League investigation.
Manchester City are fourth in the league table on 27 points after 15 games, while Palace are 16th.
Pep Guardiola's ability to bend the Premier League to his will was once questioned but the Manchester City manager has seen off the early doubters during a period of unprecedented dominance, with his latest triumph making City the first side in English football history to win four top division titles in a row.
Manchester City topped the scoring charts as they won an unprecedented fourth title in succession, their 3-1 victory over West Ham United on Sunday taking their tally to 96.
"The reality is I am closer to leaving than staying," the Spaniard told Sky News, before clarifying that there would be no immediate departure from the club he has managed since 2016.
The 23-year-old failed to add to his 27 Premier League goals on the final day but still proved decisive in the run-in to help City secure an unprecedented fourth consecutive English top-flight crown.
Phil Foden said winning will never get boring after the England international's first-half double fired Manchester City to a 3-1 victory over West Ham and an unprecedented fourth-consecutive Premier League title.
Arsenal's dreams of a first Premier League crown in 20 years were dashed as their 2-1 win against Everton was rendered irrelevant by Manchester City's title-clinching victory over West Ham.
Manchester City created English football history on Sunday, overcoming West Ham 3-1 to win their fourth straight Premier League title and break Arsenal's hearts as Jurgen Klopp made an emotional Liverpool exit.
Pep Guardiola urged history-chasing Manchester City to seize their title "destiny" as the battle for Premier League supremacy reaches a thrilling climax on Sunday.
Manchester City go into their last match against West Ham with a two-point lead, knowing that victory would secure the title for an unprecedented fourth successive season.
Foden has scored 17 goals and grabbed eight assists in 34 league games this season playing centrally as well as on the wing when needed. He has 25 goals and 11 assists in all competitions.
