Neymar was out for more than a year until last month following right knee surgery.
The Brazilian superstar lasted just 26 minutes as a second-half substitute before limping off with an apparent right hamstring strain in Monday's 3-0 AFC Champions League Elite win over Esteghlal.
The evening ended on a sour note for Al-Hilal when Neymar, who returned two weeks ago from a year out due to a ruptured cruciate ligament, was replaced 29 minutes after his introduction from the bench due to injury.
The former Barcelona and Paris Saint-Germain attacker had not played since rupturing his meniscus and anterior cruciate ligament in his left knee while on international duty in October last year.
"Happy to be back in the group," Neymar posted on Instagram, with pictures of him running and kicking the ball, watched by Al Hilal's Portuguese coach Jorge Jesus.
Brazil coach Dorival Junior called for Neymar to be given as much time as he needs to make a complete recovery from a knee injury that has sidelined him for almost a year.
Neymar is set to miss the start of the next Saudi Pro League season as he recovers from a serious knee injury, Al Hilal's coach said Tuesday.
The country of Pele, Garrincha and Ronaldinho, which once wowed the world with its 'samba' style, has not won the World Cup since 2002. Nor has it produced a Ballon d'Or winner since Kaka in 2007.
Jorge Jesus' side, top of the Saudi league and still alive in the King's Cup and Asian Champions league, are bidding for a quadruple of trophies this season.
Cristiano Ronaldo received a huge financial proposal to play in Saudi Arabia, according to TVI and CNN Portugal.
A "very optimistic" Roberto Carlos declared "it is time to win" as he backed Brazil to lift the World Cup in Qatar.
Argentina striker Lionel Messi scored five goals in a 5-0 friendly win over Estonia on Sunday, a result which helped him overtake Hungary’s great Ferenc Puskas among the all-time international top scorers.
Brazil manager Tite shot down suggestions of a rift in the Brazil camp, branding reports that forwards Richarlison and Vinicius Junior had clashed in training on Saturday as "fake news".
Brazil manager Tite said his team's "mentality" can make the difference at the World Cup, after they broke down a stubborn Japan in a 1-0 friendly win in Tokyo on Monday.
Neymar's penalty 13 minutes from time earned Brazil a 1-0 win over fellow World Cup qualifiers Japan at Tokyo's National Stadium on Monday as the Paris St Germain striker moved to within three goals of Pele's all-time national scoring record.
Brazil no longer rely on superstar Neymar to win games, manager Tite said Sunday, with an Olympic gold medal-winning generation looking to step up at the World Cup.
Neymar scored a pair of penalties to move to within four goals of Pele at the top of the country's all-time scoring list as Brazil cruised to a 5-1 win over fellow World Cup qualifiers South Korea at Seoul World Cup Stadium on Thursday.
Neymar says he would like to stay at French champions Paris Saint-Germain despite rarely justifying his world record fee of 222 million euros ($236 million) and amid rumours the club would like him to leave.
How did this crazy fandom and footballing rivalry reach Bangladesh?