Neymar was out for more than a year until last month following right knee surgery.
The Brazilian superstar lasted just 26 minutes as a second-half substitute before limping off with an apparent right hamstring strain in Monday's 3-0 AFC Champions League Elite win over Esteghlal.
The evening ended on a sour note for Al-Hilal when Neymar, who returned two weeks ago from a year out due to a ruptured cruciate ligament, was replaced 29 minutes after his introduction from the bench due to injury.
The former Barcelona and Paris Saint-Germain attacker had not played since rupturing his meniscus and anterior cruciate ligament in his left knee while on international duty in October last year.
"Happy to be back in the group," Neymar posted on Instagram, with pictures of him running and kicking the ball, watched by Al Hilal's Portuguese coach Jorge Jesus.
Brazil coach Dorival Junior called for Neymar to be given as much time as he needs to make a complete recovery from a knee injury that has sidelined him for almost a year.
Neymar is set to miss the start of the next Saudi Pro League season as he recovers from a serious knee injury, Al Hilal's coach said Tuesday.
The country of Pele, Garrincha and Ronaldinho, which once wowed the world with its 'samba' style, has not won the World Cup since 2002. Nor has it produced a Ballon d'Or winner since Kaka in 2007.
Jorge Jesus' side, top of the Saudi league and still alive in the King's Cup and Asian Champions league, are bidding for a quadruple of trophies this season.
Normal service is set to resume in France on Wednesday with Kylian Mbappe and Neymar both set to feature for leaders Paris Saint-German as they restart their Ligue 1 season, 45 days after it was popped on ice for the World Cup, with a home game against struggling Strasbourg.
Lionel Messi finally has 'his' World Cup after defeating France in a penalty shootout in one of the most exciting finals in World Cup history.
Jose Arnaldo dos Santos Junior traveled to Qatar to cheer on his beloved Brazilian national team led by Neymar in their ultimately failed attempt to claim a sixth World Cup crown.
A court in Spain on Tuesday acquitted Brazilian superstar Neymar of corruption charges related to his transfer to Barcelona from Santos in 2013.
Legendary German footballer and a member of FIFA’s Technical Study Group (TSG), Jurgen Klinsmann, opined that Brazil made a mistake by not sending their best penalty takers in their quarterfinal defeat against Croatia.
When Cristiano Ronaldo walked down the tunnel in tears at the Al Thumama Stadium on Saturday, it must have felt surreal for millions of his and Portugal fans around the globe.
Pele urged Neymar to "keep inspiring us" on Saturday after the Brazil forward dropped a retirement hint following his team's shock World Cup defeat to Croatia.
Brazil star Neymar hinted he might quit international football on Friday, saying he could not "100 percent" guarantee he would play for the national team again.
Neymar equalled Pele's record of 77 Brazil goals after scoring against Croatia in the World Cup quarter-finals on Friday.
Croatia coach Zlatko Dalic described their World Cup quarter-final opponents Brazil as "terrifying" after the five-time champions thrashed South Korea 4-1 to send a clear message to their rivals.