With Roger Federer retired and Rafael Nadal struggling to get back on court due to injuries, Novak Djokovic was the last man of that golden generation standing at Flushing Meadows, but the Serb crashed out in the third round to Australian Alexei Popyrin.
Jannik Sinner produced a brutal display of baseline power as he became the first Italian man to win the US. Open with a 6-3, 6-4, 7-5 win over American Taylor Fritz in the final on Sunday.
"I'm speechless right now. So many times I thought I was so close to get the US Open title. It has always been a dream of mine and finally I got this beautiful trophy," said Sabalenka.
Frances Tiafoe blamed his heartbreaking five-set US Open semi-final defeat to Taylor Fritz on cramping after his "body shut down".
Taylor Fritz fought back to defeat compatriot Frances Tiafoe at the US Open on Friday, becoming the first American man to reach a Grand Slam final in 15 years.
Italian top seed Jannik Sinner took down ailing Briton Jack Draper 7-5, 7-6 (7/3), 6-2 to reach the US Open final on Friday, overcoming muggy conditions in a chaotic match at Arthur Ashe Stadium.
World number one Jannik Sinner reached his first US Open semi-final on Wednesday with a four-set victory over 2021 champion and two-time runner-up Daniil Medvedev.
Jessica Pegula became the fourth American to reach this year's US Open semifinals on Wednesday by stunning world number one Iga Swiatek as Jack Draper broke through to his first Grand Slam last-four.
Top seed Swiatek, who won the title two years ago, showcased her all-court game in a straightforward 6-4, 6-1 win over Russian Liudmila Samsonova to open the evening session at Arthur Ashe Stadium and warned she was only going to improve.
Novak Djokovic and Rafael Nadal get their US Open campaigns under way Monday in the shadow of Arthur Ashe Stadium's spectacular $150 million retractable roof and alongside rock music legend Phil Collins.
Roger Federer pulls out of the Rio Olympics and will miss the rest of the season, including the U.S. Open, because he needs "more extensive rehabilitation" to prolong his career after knee surgery earlier this year.
The 2016 US Open, the fourth and final Grand Slam of the year, will dish out a record $46.3 million in prize money, including $3.5 million for the men's and women's singles champions.
Dustin Johnson has claimed his first major - but only after a farcical end to the US Open that drew criticism from Rory McIlroy and Jordan Spieth.
The moment Novak Djokovic accepted that being part of the Roger Federer/Rafael Nadal era was a chance, not a curse, everything improved for him. After winning his first French Open title, world's number one tennis player holds all four grand slams at the same time.
Martina Hingis and Sania Mirza claimed their second straight Grand Slam title in the US Open women's doubles.
Novak Djokovic clinched his third Grand Slam title of 2015 and 10th career major with a 6-4, 5-7, 6-4, 6-4 triumph over sentimental favorite Roger Federer in the US Open final.
New York police releases video footage of the mistaken arrest of retired professional tennis player James Blake.
"Fantastic Friday" at the US Open sees Serena Williams, Novak Djokovic and Roger Federer in starring roles.
Serena Williams defeats her sister Venus at the US Open to move within two victories of her first calendar Grand Slam.