With Roger Federer retired and Rafael Nadal struggling to get back on court due to injuries, Novak Djokovic was the last man of that golden generation standing at Flushing Meadows, but the Serb crashed out in the third round to Australian Alexei Popyrin.
Jannik Sinner produced a brutal display of baseline power as he became the first Italian man to win the US. Open with a 6-3, 6-4, 7-5 win over American Taylor Fritz in the final on Sunday.
"I'm speechless right now. So many times I thought I was so close to get the US Open title. It has always been a dream of mine and finally I got this beautiful trophy," said Sabalenka.
Frances Tiafoe blamed his heartbreaking five-set US Open semi-final defeat to Taylor Fritz on cramping after his "body shut down".
Taylor Fritz fought back to defeat compatriot Frances Tiafoe at the US Open on Friday, becoming the first American man to reach a Grand Slam final in 15 years.
Italian top seed Jannik Sinner took down ailing Briton Jack Draper 7-5, 7-6 (7/3), 6-2 to reach the US Open final on Friday, overcoming muggy conditions in a chaotic match at Arthur Ashe Stadium.
World number one Jannik Sinner reached his first US Open semi-final on Wednesday with a four-set victory over 2021 champion and two-time runner-up Daniil Medvedev.
Jessica Pegula became the fourth American to reach this year's US Open semifinals on Wednesday by stunning world number one Iga Swiatek as Jack Draper broke through to his first Grand Slam last-four.
Top seed Swiatek, who won the title two years ago, showcased her all-court game in a straightforward 6-4, 6-1 win over Russian Liudmila Samsonova to open the evening session at Arthur Ashe Stadium and warned she was only going to improve.
Former US Open champ Juan Martin Del Potro got his season off to another successful start at the Delray Beach Open, defeating Kevin Anderson in straight sets and overcoming an opening set tumble in the process.
Serena Williams suffered a shock second-round defeat at the Auckland Classic Wednesday following her sister Venus's earlier withdrawal with an arm injury.
Karolina Pliskova vowed not to turn her back on her all-or-nothing game despite it falling short in her three-set defeat to Angelique Kerber in Saturday's US Open final.
A fantastic year: 2 Grand Slams, Olympic silver medallist, new World No. 1! Congrats, @AngeliqueKerber #USOpen
Germany's Angelique Kerber began her reign as world number one in imperious style battling past a determined Karolina Pliskova 6-3, 4-6, 6-4 to win the US Open final on Saturday and claim her second grand slam title of the year.
Novak Djokovic scraps his way into the U.S. Open final for a seventh time with a confounding 6-3 6-2 3-6 6-2 win over enigmatic Frenchman Gael Monfils.
Reaching top of the world seems to agree with Angelique Kerber, who celebrates her ascension to the number one ranking with a 6-4 6-3 win over Caroline Wozniacki to advance to the U.S. Open final.
Serena Williams crashes out of the US Open, her semi-final defeat to Karolina Pliskova costing her a shot at a 23rd Grand Slam title.
World number one Serena Williams fends off spirited Simona Halep, downing the fifth-seeded Romanian 6-2, 4-6, 6-3 to reach the US Open semi-finals.
Swiss third seed Stan Wawrinka outlasts tiring former champion Juan Martin del Potro in four sets to advance to the semi-finals of the U.S. Open.