A brace from Amad Diallo gave United their first success in this season's competition, coming under interim manager Ruud van Nistelrooy after they had drawn the previous three games with Erik ten Hag was in charge.
Tottenham Hotspur made it three wins from three in the Europa League with a 1-0 win at home to AZ on Thursday but Manchester United remain winless after being held to a 1-1 draw at red-carded Jose Mourinho's Fenerbahce.
Manchester United manager Erik ten Hag has highlighted a lack of goals as the major factor behind the English giants' faltering start to the season.
Manchester United manager Erik ten Hag said his side had failed to maintain their intensity in Wednesday's 1-1 Europa League draw with FC Twente and should have pushed to kill the visitors off before they had the chance to equalise.
Erik ten Hag made a convincing case to be spared the sack as Manchester United upset Manchester City to take the FA Cup with a shock 2-1 victory in Saturday's final.
Leverkusen - or 'Neverlusen' as they had been dubbed after obliterating Bayern Munich's 11-year Bundesliga title monopoly in Germany - can still win a domestic double with victory against second-tier Kaiserslautern in Saturday's German Cup final.
Gian Piero Gasperini lavished praise on his "incredible" Atalanta players after they stunned Bayer Leverkusen to win the Europa League and claim their first ever continental honour.
Ademola Lookman scored a stunning hattrick as Atalanta ended Bayer Leverkusen's 51-match unbeaten run to win the Europa League final 3-0 on Wednesday and claim their first trophy for 61 years.
Bayer Leverkusen had won only two major trophies in their 119-year history before this season but on Wednesday the newly-crowned Bundesliga champions have the chance to claim a double when they face Atalanta in the Europa League final in Dublin.
Manchester United avoided further embarrassment after their humiliating defeat to Manchester City by coming from behind to beat Cypriots Omonia Nicosia 3-2 in the Europa League on Thursday, while Premier League leaders Arsenal eased past Bodo/Glimt.
Jadon Sancho and Cristiano Ronaldo gave timely reminders of their value with both on target as Manchester United got their Europa League campaign back on track with a 2-0 victory at Moldovan side Sheriff Tiraspol on Thursday.
Manchester United kicked off their Europa League campaign poorly with a 1-0 home defeat by Real Sociedad as Arsenal's new signing Marquinhos scored in a 2-1 win at FC Zurich on Thursday.
Chelsea hammered their London rivals Arsenal 4-1 to win the Europa League thanks to two goals from Eden Hazard, possibly making his last appearance for the Blues, and one apiece for Olivier Giroud and Pedro.
Manchester United's Paul Pogba takes a step towards helping repay his world record transfer fee with the opening goal in their Europa League win over Ajax Amsterdam.
Though he denies it, Manchester United manager Jose Mourinho has gambled the club's season on the outcome of Wednesday's Europa League final against Ajax in Stockholm.
Ajax Amsterdam produced a performance worthy of the club's illustrious past when they crushed Olympique Lyonnais 4-1 on Wednesday to move to the brink of their first European final since 1996.
Manchester United striker Zlatan Ibrahimovic has vowed to come back even stronger after suffering a serious knee injury against Anderlecht in Europa League last week.
At least seven football fans were killed and 11 injured when an electric cable fell on a building where they were watching a Europa League match, Nigerian police said Friday.
Manchester United manager Jose Mourinho said he was preparing for bad news after losing Zlatan Ibrahimovic and Marcos Rojo to injury during his side's Europa League quarterfinal success against Anderlecht.