Neymar was out for more than a year until last month following right knee surgery.
The Brazilian superstar lasted just 26 minutes as a second-half substitute before limping off with an apparent right hamstring strain in Monday's 3-0 AFC Champions League Elite win over Esteghlal.
The evening ended on a sour note for Al-Hilal when Neymar, who returned two weeks ago from a year out due to a ruptured cruciate ligament, was replaced 29 minutes after his introduction from the bench due to injury.
The former Barcelona and Paris Saint-Germain attacker had not played since rupturing his meniscus and anterior cruciate ligament in his left knee while on international duty in October last year.
"Happy to be back in the group," Neymar posted on Instagram, with pictures of him running and kicking the ball, watched by Al Hilal's Portuguese coach Jorge Jesus.
Brazil coach Dorival Junior called for Neymar to be given as much time as he needs to make a complete recovery from a knee injury that has sidelined him for almost a year.
Neymar is set to miss the start of the next Saudi Pro League season as he recovers from a serious knee injury, Al Hilal's coach said Tuesday.
The country of Pele, Garrincha and Ronaldinho, which once wowed the world with its 'samba' style, has not won the World Cup since 2002. Nor has it produced a Ballon d'Or winner since Kaka in 2007.
Jorge Jesus' side, top of the Saudi league and still alive in the King's Cup and Asian Champions league, are bidding for a quadruple of trophies this season.
Neymar starred on his PSG return with two goals and two assists and coach Unai Emery says that if someone likes football they are bound to be happy to see a player like Neymar.
Barca defender Gerard Pique says that he understood the reason for Neymar leaving Barcelona and suggests that he is still good friends with the Brazilian.
Burglars rob signed Neymar shirts and other valuables from PSG coach Unai Emery's house.
Paris Saint-Germain are hoping Neymar will return from Brazil in three or four days after he travelled home for personal reasons, coach Unai Emery says.
Cristiano Ronaldo's Real Madrid are to face Neymar's Paris Saint Germain while Barca and Chelsea renew old rivalries in the last 16 of the Champions League.
Paris Saint-Germain star Neymar is urgently travelling to Brazil due to "personal matters", the Brazilian company that manages the footballer's career says.
Real Madrid president Florentino Perez opens the door for Neymar to join the European champions by declaring it would help further the forward's individual ambitions.
Barcelona’s star strike Luis Suarez opens up regarding Neymar’s move to PSG and suggests that he does not think that Neymar would move to Real Madrid.
The 2018 FIFA World Cup draw is set to take place on December 1 where the 32 competing nations will discover their fate and star players like Messi, Neymar and Ronaldo are also looking forward to the draw.
Edinson Cavani and Neymar are both on target as Paris Saint-Germain edge champions Monaco 2-1 to climb nine points clear atop France's Ligue 1.