Neymar was out for more than a year until last month following right knee surgery.
The Brazilian superstar lasted just 26 minutes as a second-half substitute before limping off with an apparent right hamstring strain in Monday's 3-0 AFC Champions League Elite win over Esteghlal.
The evening ended on a sour note for Al-Hilal when Neymar, who returned two weeks ago from a year out due to a ruptured cruciate ligament, was replaced 29 minutes after his introduction from the bench due to injury.
The former Barcelona and Paris Saint-Germain attacker had not played since rupturing his meniscus and anterior cruciate ligament in his left knee while on international duty in October last year.
"Happy to be back in the group," Neymar posted on Instagram, with pictures of him running and kicking the ball, watched by Al Hilal's Portuguese coach Jorge Jesus.
Brazil coach Dorival Junior called for Neymar to be given as much time as he needs to make a complete recovery from a knee injury that has sidelined him for almost a year.
Neymar is set to miss the start of the next Saudi Pro League season as he recovers from a serious knee injury, Al Hilal's coach said Tuesday.
The country of Pele, Garrincha and Ronaldinho, which once wowed the world with its 'samba' style, has not won the World Cup since 2002. Nor has it produced a Ballon d'Or winner since Kaka in 2007.
Jorge Jesus' side, top of the Saudi league and still alive in the King's Cup and Asian Champions league, are bidding for a quadruple of trophies this season.
Brazilian forward Neymar, who scored PSG's second goal in the 17th minute, left the field in tears early in the second half after colliding with Lille's Benjamin Andre and rolling his ankle
The visitors were punished when Mbappe turned in Juan Bernat's cross to make it 3-3 before Messi's free-kick five minutes into stoppage time sealed a dramatic victory for PSG.
PSG head coach Galtier noted Neymar played in a poker tournament on Wednesday and visited a McDonald's branch with friends. It came at a point when PSG's season has reached crisis point, with three damaging defeats in succession putting Galtier under pressure.
Bayern Munich visit the French capital for the first leg of their Champions League last-16 tie next Tuesday, but there will be no easy build-up to that game for PSG.
Neymar da Silva Santos Junior has won the Samba Gold award, also known as Samba d'Or, and it is the sixth time the Brazilian playmaker bagged the prize in nine years.
Paris St Germain head coach Christophe Galtier said injuries sustained by Sergio Ramos and Kylian Mbappe in their 3-1 win at Montpellier on Wednesday were not serious and that they were taken off to manage their workload during a busy schedule.
South America's top national team competition, the Copa America, will be held in the United States in 2024 and feature 10 teams from South America's CONMEBOL and six teams from the CONCACAF region.
Lionel Messi will be rested for Paris St Germain's French Cup game at third division side Chateauroux as the Argentine forward needs more time to recover from his world Cup winning campaign, coach Christophe Galtier said on Thursday.
Football legend Pele, who died Thursday at the age of 82, "transformed football into an art," said Brazil and Paris Saint-Germain superstar Neymar in a tribute to his country's greatest sporting icon.
An injury-time penalty from Kylian Mbappe sealed a last-gasp 2-1 win for Paris Saint-Germain over modest Strasbourg in Ligue 1 on Wednesday after Neymar had been sent off.