For a club sitting 14th in the Premier League and sleepwalking towards their worst-ever points haul, this second-tier continental competition has become the only show in town.
Nowhere will those celebrations be bigger than inside the Arctic Circle in Bodo, where fans will now be preparing for a semi-final against English Premier League side Tottenham Hotspur after one of the greatest nights in Norwegian sport.
United's season looked over when Lyon came from 2-0 down to lead by two goals with just six minutes remaining at Old Trafford despite having captain Corentin Tolisso sent off.
Andre Onana will be recalled for Manchester United's season-defining Europa League quarter-final second leg against Lyon after his costly goalkeeping errors in the first leg, manager Ruben Amorim confirmed on Wednesday.
Manchester United goalkeeper Andre Onana has been dropped for Sunday’s Premier League match at Newcastle United after his mistakes led to both Olympique Lyon goals in a 2-2 draw in their Europa League quarter-final first leg on Thursday, British media said.
Manchester United captain Bruno Fernandes said it is not the players' fault for the contracts signed off by the club as he hit back at claims by co-owner Jim Ratcliffe that some are "overpaid".
Wayne Rooney thinks former side Manchester United look "lost" and "scared" on the pitch and that "10 to 15 players need to leave the club".
Real Sociedad's Mikel Oyarzabal coolly netted a penalty to hold Manchester United to a 1-1 draw in a Europa League last 16 first leg clash on Thursday.
Manchester United were drawn Friday to play Real Sociedad of Spain in the last 16 of this season's Europa League, while Rangers will take on Jose Mourinho's Fenerbahce, and Tottenham Hotspur face AZ Alkmaar.
Mohamed Salah has given Liverpool a major boost after the Egypt star travelled to Sparta Prague for Thursday's Europa League clash following his recent injury lay-off.
AC Milan, meanwhile, were drawn against French club Rennes.
A youthful Liverpool side lost 2-1 at Union Saint-Gilloise in their final Europa League group game on Thursday, while Villarreal snatched a place in the last 16 from Rennes with a dramatic victory in France.
Jurgen Klopp's side sealed top spot in Group E thanks to Gakpo's brace and goals from Luis Diaz and Mohamed Salah at Anfield.
Brighton's "incredible" journey from homeless exiles facing oblivion to their current status as Premier League trendsetters will reach a memorable climax when they host AEK Athens in their first-ever European match on Thursday.
Liverpool were handed a kind draw on Friday for this season's Europa League group stage while their Premier League rivals Brighton and Hove Albion can look forward to meeting European giants Ajax and Marseille in their first ever foray into continental competition.
“I thank you for the invitation to join the UEFA Football Board, but I regret to inform you that I will be relinquishing my involvement with immediate effect,” Mourinho wrote in a letter to UEFA director and former AC Milan chairman Zvonimir Boban.
His message was one of pride, which is what he has restored at Roma, a team which has one of Italy's largest, most passionate fan bases but has won little of note since being founded in 1927.
Jose Mourinho threw his future as Roma manager into further doubt on Wednesday, saying he was "too tired" after the bitter pain of losing his first major European final to Sevilla.
Sevilla beat AS Roma 4-1 on penalties on Wednesday to win the Europa League for a record-extending seventh time, handing Jose Mourinho his first defeat in six European finals.
